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Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Middle Region) Peptide

CASP4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN2184292
发货至: 中国
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Quick Overview for Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Middle Region) Peptide (ABIN2184292)

抗原

Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

宿主

资源

  • 8
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    CGTVHDEKKP DVLLYDTIFQ IFNNRNCLSL KDKPKVIIVQ ACRGANRGEL

    产品特性

    This is a synthetic peptide designed for use in combination with anti-CASP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

    背景

    This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

    Alias Symbols: ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX

    Protein Size: 321

    分子量

    35 kDa

    基因ID

    837

    NCBI登录号

    NM_033306, NP_150649
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