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Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (N-Term) Peptide

CASP4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5673017
发货至: 中国
  • 抗原 See all Caspase 4 (CASP4) products
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    蛋白结构域
    N-Term
    宿主
    资源
    • 8
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    KKPLKVLESL GKDFLTGVLD NLVEQNVLNW KEEEKKKYYD AKTEDKVRVM
    产品特性
    This is a synthetic peptide designed for use in combination with anti- CASP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    别名
    ICE(rel)II Peptide, ICEREL-II Peptide, ICH-2 Peptide, Mih1/TX Peptide, TX Peptide, Casp11 Peptide, CASP13 Peptide, CASP1 Peptide, CASP4 Peptide, Caspl Peptide, ich-3 Peptide, Casp4 Peptide, caspase 4 Peptide, caspase 4, apoptosis-related cysteine peptidase Peptide, caspase-4 Peptide, CASP4 Peptide, Casp4 Peptide, LOC100731032 Peptide
    背景
    This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

    Alias Symbols: TX, ICH-2, Mih1/TX, ICEREL-II, ICE(rel)II

    Protein Size: 116
    基因ID
    837
    NCBI登录号
    NM_001225, NP_001216
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