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PEX19 产品

(Peroxisomal Biogenesis Factor 19 (PEX19))

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This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010].

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Featured PEX19 Categories

PEX19 抗体

High quality antibodies with extensive validation data.

PEX19 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PEX19 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (5)
Cat. No. ABIN2856772
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN519560
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN6145463
Quantity 100 μL
Datasheet Datasheet

Recommended PEX19 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231795
Quantity 96 tests
Datasheet Datasheet

Recommended PEX19 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124370
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314699
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085862
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PEX19 Products

Zhou, Yu, Arshad, Wang, Lu, Gong, Gu, Li, Xu: "Coordination Among Lipid Droplets, Peroxisomes, and Mitochondria Regulates Energy Expenditure Through the CIDE-ATGL-PPARα Pathway in Adipocytes." in: Diabetes, Vol. 67, Issue 10, pp. 1935-1948, (2018) (PubMed).

Mayerhofer, Kattenfeld, Roscher, Muntau: "Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly." in: Biochemical and biophysical research communications, Vol. 291, Issue 5, pp. 1180-6, (2002) (PubMed).

Gloeckner, Mayerhofer, Landgraf, Muntau, Holzinger, Gerber, Kammerer, Adamski, Roscher: "Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p." in: Biochemical and biophysical research communications, Vol. 271, Issue 1, pp. 144-50, (2000) (PubMed).

Synonyms and alternative names related to PEX19

Peroxin 19 (Pex19), Peroxisomal farnesylated protein (Bm1_19905), peroxisomal biogenesis factor 19 (PEX19), peroxisomal biogenesis factor 19 (Pex19), BEST:GH03076, CG5325, D1S2223E, DmelPex19, Dmel\\CG5325, HK33, PBD12A, Peroxin-19, PMP1, PMPI, PXF, Pxf, PxF, PXMP1

Protein level used designations for PEX19

  • CG5325-PA
  • CG5325-PB
  • Pex19-PA
  • Pex19-PB
  • peroxin 19
  • peroxisomal farnesylated protein
  • Peroxisomal farnesylated protein
  • 33 kDa housekeeping protein
  • housekeeping gene, 33kD
  • peroxin-19
  • peroxisome biogenesis factor 19
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