PEN2 抗体
(Presenilin Enhancer 2 Homolog (PSENEN))
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant PEN2 抗体 (Alexa Fluor 405) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| PEN2 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant PEN2 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| PEN2 抗体 (AA 51-101) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 405
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 555
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 51-101
Latest Publications for our PEN2 抗体
: "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 4, pp. 258-66, (2015) (PubMed).
: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 7850-4, (2003) (PubMed).
: "Membrane topology of gamma-secretase component PEN-2." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 20117-23, (2003) (PubMed).
: "The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).
: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." in: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).
: "aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation." in: Developmental cell, Vol. 3, Issue 1, pp. 85-97, (2002) (PubMed).
: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 7850-4, (2003) (PubMed).
: "Membrane topology of gamma-secretase component PEN-2." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 20117-23, (2003) (PubMed).
: "The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).
: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." in: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).
: "aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation." in: Developmental cell, Vol. 3, Issue 1, pp. 85-97, (2002) (PubMed).
Aliases for PEN2 抗体
presenilin enhancer gamma-secretase subunit (PSENEN) 抗体presenilin enhancer 2 (PEN2) 抗体
presenilin enhancer 2 (Psenen) 抗体
presenilin enhancer gamma secretase subunit (Psenen) 抗体
Gamma-secretase subunit pen-2 (pen-2) 抗体
presenilin enhancer (pen-2) 抗体
presenilin enhancer gamma secretase subunit S homeolog (psenen.S) 抗体
presenilin enhancer gamma secretase subunit (psenen) 抗体
presenilin enhancer gamma-secretase subunit (Psenen) 抗体
1700023M09Rik 抗体
ACYPI006208 抗体
anon-AE003800.1 抗体
CG33198 抗体
Dmel\\CG33198 抗体
dPen-2 抗体
MSTP064 抗体
PEN-2 抗体
Pen-2 抗体
pen-2 抗体
PEN2 抗体
pen2 抗体
Psenen 抗体
psenen 抗体
RGD1312037 抗体
zgc:109727 抗体
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