(serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011].
Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).
Zhang, Dai, Neng, Zhang, Zhi, Fridberger, Shi: "Perivascular macrophage-like melanocyte responsiveness to acoustic trauma--a salient feature of strial barrier associated hearing loss." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 9, pp. 3730-40, (2013) (PubMed).
Aliases for PEDF 蛋白
serpin family F member 1 (SERPINF1) 蛋白 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) 蛋白 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog (serpinf1.L) 蛋白 serpin family F member 1 (Serpinf1) 蛋白 serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) 蛋白 AI195227 蛋白 Dmrs91 蛋白 EPC-1 蛋白 MGC82984 蛋白 OI6 蛋白 OI12 蛋白 PEDF 蛋白 Pedf 蛋白 Pedfl 蛋白 Sdf3 蛋白 SERPINF1 蛋白 zgc:92072 蛋白