PDX1 抗体
(Pancreatic and Duodenal Homeobox 1 (PDX1))
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008].
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Latest Publications for our PDX1 抗体
: "Low-Level Insulin Content Within Abundant Non-β Islet Endocrine Cells in Long-standing Type 1 Diabetes." in: Diabetes, Vol. 68, Issue 3, pp. 598-608, (2019) (PubMed).: "Possible role of miR-2909 RNomics in arsenic mediated pancreatic β-cell dysfunction." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 50, pp. 263-267, (2019) (PubMed).
: "Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 375-382, (2018) (PubMed).
: "Isolation and Characterization of Pancreatic Canine Fetal Cells at the Final Stage of Gestation." in: Anatomical record (Hoboken, N.J. : 2007), (2018) (PubMed).
: "Highly Proliferative α-Cell-Related Islet Endocrine Cells in Human Pancreata." in: Diabetes, Vol. 67, Issue 4, pp. 674-686, (2018) (PubMed).
: "Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells." in: BioMed research international, Vol. 2017, pp. 2501578, (2017) (PubMed).
: "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." in: Scientific reports, Vol. 6, pp. 37414, (2016) (PubMed).
: "Generation of insulin-producing cells from C3H10T1/2 mesenchymal progenitor cells." in: Gene, Vol. 562, Issue 1, pp. 107-16, (2015) (PubMed).
: "Interferon-? Decreases Nuclear Localization of Pdx-1 and Triggers ?-Cell Dysfunction in Chronic Pancreatitis." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 7, pp. 523-9, (2015) (PubMed).
: "Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion." in: Science (New York, N.Y.), Vol. 350, Issue 6261, pp. aac4250, (2015) (PubMed).
Aliases for PDX1 抗体
pancreatic and duodenal homeobox 1 (PDX1) 抗体pancreatic and duodenal homeobox 1 (pdx1) 抗体
pancreatic and duodenal homeobox 1 (Pdx1) 抗体
pancreatic and duodenal homeobox 1 S homeolog (pdx1.S) 抗体
GSF 抗体
IDX-1 抗体
Idx1 抗体
IPF-1 抗体
IPF1 抗体
ipf1 抗体
Ipf1 抗体
IUF1 抗体
MODY4 抗体
Mody4 抗体
PDX-1 抗体
pdx-1 抗体
PDX1 抗体
STF-1 抗体
Stf1 抗体
XlHbox-8 抗体
xlhbox8 抗体
zgc:100874 抗体
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