(PDS5, Regulator of Cohesion Maintenance, Homolog B (PDS5B))
This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, May 2010].
Brough, Bajrami, Vatcheva, Natrajan, Reis-Filho, Lord, Ashworth: "APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer." in: The EMBO journal, Vol. 31, Issue 5, pp. 1160-76, (2012) (PubMed).
Aliases for PDS5B 抗体
PDS5 cohesin associated factor B (PDS5B) 抗体 PDS5 cohesin associated factor B (Pds5b) 抗体 PDS5 cohesin associated factor B (pds5b) 抗体 PDS5 cohesin associated factor B L homeolog (pds5b.L) 抗体 AI646570 抗体 APRIN 抗体 Aprin 抗体 aprin 抗体 AS3 抗体 as3 抗体 AW212954 抗体 CG008 抗体 mKIAA0979 抗体 pds5b 抗体