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PDHA1 产品

(Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Categories

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle.

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Featured PDHA1 Categories

PDHA1 抗体

High quality antibodies with extensive validation data.

PDHA1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PDHA1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDHA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB
Validations
  • collections(7)
Cat. No. ABIN3023697
Quantity 100 μL
Reactivity Human
Application IHC (p), WB
Validations
  • collections(6)
Cat. No. ABIN518747
Quantity 50 μg

Application WB
Validations
  • collections(3)
Cat. No. ABIN2783236
Quantity 100 μL

Recommended PDHA1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • collections(1)
Cat. No. ABIN6969793
Quantity 96 tests
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • collections(1)
Cat. No. ABIN6959003
Quantity 96 tests
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • collections(1)
Cat. No. ABIN6959004
Quantity 96 tests

Recommended PDHA1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • collections(1)
Cat. No. ABIN3084868
Quantity 1 mg
Reactivity Mouse
Source Insect Cells
Validations
  • collections(1)
Cat. No. ABIN3133856
Quantity 1 mg
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • collections(1)
Cat. No. ABIN2006268
Quantity 100 μg

Latest Publications on our PDHA1 Products

Zhuang, Ly, Frazier, Yu, Qin, Fan, Goetz, Boughey, Weinshilboum, Wang: "The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer." in: Cancer & metabolism, Vol. 7, pp. 1, (2019) (PubMed).

Menk, Scharping, Moreci, Zeng, Guy, Salvatore, Bae, Xie, Young, Wendell, Delgoffe: "Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions." in: Cell reports, Vol. 22, Issue 6, pp. 1509-1521, (2019) (PubMed).

Zhong, Xu, Li, Zhu, Cao, Li, Chen, Hu, Li, Luo, Pan, Zhang, Lai, Wang, Du, Chen, Xu, Olkkonen, Lei, Xu, Yan: "ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells." in: Cell reports, Vol. 26, Issue 8, pp. 2166-2177.e9, (2019) (PubMed).

Thapa, Zhang, Manning, Guimarães, Stoner, Lai, Shiva, Scott: "Loss of GCN5L1 in cardiac cells limits mitochondrial respiratory capacity under hyperglycemic conditions." in: Physiological reports, Vol. 7, Issue 8, pp. e14054, (2019) (PubMed).

Thapa, Wu, Stoner, Xie, Zhang, Manning, Lu, Li, Chen, Gucek, Playford, Mehta, Harmon, ODoherty, Jurczak, Sack, Scott: "The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA." in: The Journal of biological chemistry, Vol. 293, Issue 46, pp. 17676-17684, (2018) (PubMed).

Gao, Zhou, Ren, Kim, He, Seo, Guillot, Ding, Wu, Shao, Wang, Zhang, Wang, Feng, Xu, Han, Zhong, Zhou, Pacher, Niu, Gao: "Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids." in: Gut, (2018) (PubMed).

Kwong, Huo, Bround, Boyer, Schwanekamp, Ghazal, Maxwell, Jang, Khuchua, Shi, Bers, Davis, Molkentin: "The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle." in: JCI insight, Vol. 3, Issue 22, (2018) (PubMed).

Deng, Deng, Hao, Wu, Gao, Tang, Tang: "MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4." in: Experimental cell research, Vol. 373, Issue 1-2, pp. 171-179, (2018) (PubMed).

Lemecha, Morino, Imamura, Iwasaki, Ohashi, Ida, Sato, Sekine, Ugi, Maegawa: "MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 15096, (2018) (PubMed).

Bhosale, Sharpe, Koh, Kouli, Szabadkai, Duchen: "Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics." in: Biochimica et biophysica acta, Vol. 1864, Issue 6, pp. 1009-1017, (2017) (PubMed).

Synonyms and alternative names related to PDHA1

pyruvate dehydrogenase E1 alpha 1 subunit (PDHA1), pyruvate dehydrogenase E1 alpha 1 (Pdha1), pyruvate dehydrogenase E1 alpha 1 subunit (Pdha1), pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), pyruvate dehydrogenase E1 alpha 1 subunit (pdha1), pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene (LOC719277), 2-oxo acid dehydrogenase (VNG_RS07485), pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha (RR_RS04695), pyruvate dehydrogenase alpha subunit protein (pdhA1), pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit (pdhA1), precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit (PDHA1), pyruvate dehydrogenase (PDHA1), pyruvate dehydrogenase E1 alpha 1 subunit b (pdha1b), pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog (pdha1.S), PDHA, pdha, Pdha-1, Pdha1, pdha1-a, pdha1-b, PDHCE1A, pdhce1a, PHE1A, phe1a, wu:fp73b04, zgc:92705

Protein level used designations for PDHA1

  • PDHE1-A type I
  • pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
  • pyruvate dehydrogenase complex, E1-alpha polypeptide 1
  • pyruvate dehydrogenase E1alpha subunit
  • pyruvate dehydrogenase E1 alpha 1
  • pyruvate dehydrogenase E1 component alpha subunit
  • pyruvate dehydrogenase alpha 1
  • pyruvate dehydrogenase (lipoamide) alpha 1
  • PdhA1
  • pyruvate dehydrogenase alpha subunit
  • pyruvate dehydrogenase E1 component subunit alpha
  • pyruvate dehydrogenase alpha subunit protein
  • pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit
  • precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit
  • pyruvate dehydrogenase
  • Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
  • pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like
  • fp73b04
  • pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog
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