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PYM 产品

(Partner of Y14 and mago (WIBG))

Categories

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post- transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).

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Featured PYM Categories

PYM 抗体

High quality antibodies with extensive validation data.

PYM 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PYM 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (3)
Cat. No. ABIN5590928
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6750448
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Horse, Human, Monkey, Pig, Xenopus laevis
Application WB
Validations
  • (1)
Cat. No. ABIN6746847
Quantity 100 μL
Datasheet Datasheet

Recommended PYM 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325328
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3126033
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1097293
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PYM Products

Li, Johnson, Truong, Kim, Weinbren, Dittmar, Shah, Von Dollen, Newton, Jang, Krogan, Cherry, Ramage: "Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection." in: Nature microbiology, Vol. 4, Issue 6, pp. 985-995, (2019) (PubMed).

Sun, Boxer, Ransohoff, Siprashvili, Qu, Lopez-Pajares, Hollmig, Khavari: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." in: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).

Synonyms and alternative names related to PYM

Partner of Y14 and Mago (Pym), Wibg protein (wibg), PYM homolog 1, exon junction complex associated factor L homeolog (pym1.L), PYM homolog 1, exon junction complex associated factor (PYM1), PYM homolog 1, exon junction complex associated factor (Pym1), PYM homolog 1, exon junction complex associated factor (pym1), A030010B05Rik, BEST:HL05757, CG10330, CG30176, Dmel\\CG30176, PYM, Pym, UD3, zgc:65891, zgc:77281

Protein level used designations for PYM

  • CG30176-PA
  • undefined 3
  • wibg-PA
  • Protein wibg homolog
  • partner of Y14 and mago
  • protein wibg homolog
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