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抗Human PAG1 抗体:
抗Rat (Rattus) PAG1 抗体:
抗Mouse (Murine) PAG1 抗体:
Human Monoclonal PAG1 Primary Antibody for FACS, IHC (p) - ABIN94272
Yerly, Ding, Tauzin, van Echten-Deckert, Borisch, Hoessli: The sphingolipid-rich rafts of ALK+ lymphomas downregulate the Lyn-Cbp/PAG signalosome. in European journal of haematology 2010
Show all 6 Pubmed References
Human Monoclonal PAG1 Primary Antibody for IHC (p), IP - ABIN94270
Baumgartner, Angelisová, Setterblad, Mooney, Werling, Horejsí, Langsley: Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes. in Blood 2003
Show all 5 Pubmed References
Cow (Bovine) Monoclonal PAG1 Primary Antibody for IHC (p), IP - ABIN269119
Yamashita, Chattopadhyay, Fensterl, Zhang, Sen: A TRIF-independent branch of TLR3 signaling. in Journal of immunology (Baltimore, Md. : 1950) 2012
Low PAG1 expression is associated neuroblastoma (显示 ARHGEF16 抗体).
Our study highlights the underlying mechanism of cross interaction between ASCs and breast cancer cells, and indicates that PAG1/Cbp in breast cancer cell may modulate tumor progression and acquired chemoresistance in the ASCs-associated breast cancer microenvironment through Src (显示 SRC 抗体) and AKT (显示 AKT1 抗体)/mTOR (显示 FRAP1 抗体) pathways.
Up-regulated expression of CBP (显示 CREBBP 抗体) in Jurkat cells could reduce cell homogeneity and promote cell apoptosis
No association Pag1 mutation with patient with Schizophrenia.
The risk-associated allele of rs2370615 predisposes to allergic disease by increasing PAG1 expression, which might promote B cell activation (显示 BLNK 抗体) and have a pro-inflammatory effect.
CBP (显示 CREBBP 抗体) may decrease the metastasis of esophageal carcinoma by inhibiting the activation of Src (显示 SRC 抗体).
The inhibitory function of novobiocin in disrupting the HIF1alpha (显示 HIF1A 抗体)/p300 (显示 EP300 抗体) complex might be important in tumor cell growth.
siRNA directed against PAG1 in a radioresistant (Hep-2max) cell line dramatically enhanced the radiosensitivity and IR-induced cell death.
expression of CBP (显示 CREBBP 抗体) gene is decreased in esophageal carcinoma, which might contribute to the tumorigenesis and progression.
An over-expression of PAG1 in PC-3M-1E8 cells effectively suppresses the activation of Ras and ERK (显示 EPHB2 抗体), as well as the cyclin D1 (显示 CCND1 抗体) expression, leading to an inhibition of the proliferation ability of tumor cells.
Inducible knockdown of PAPP-A (显示 PAPPA 抗体) gene expression in adult female mice extends life span.
Intrinsic mitochondrial oxidative capacity was significantly increased in skeletal muscle of aged PAPP-A (显示 PAPPA 抗体) KO compared to WT mice. Moreover, 18-month-old PAPP-A (显示 PAPPA 抗体) KO mice exhibited significantly enhanced endurance running on a treadmill. Thus, PAPP-A (显示 PAPPA 抗体) deficiency in mice is associated with indices of healthy skeletal muscle function with age.
our findings illustrate that Cbp (显示 CREBBP 抗体) is an important regulator of Csk (显示 CSK 抗体) recruitment to the SFK Lyn (显示 LYN 抗体) in Eporesponsive erythroid cells.
Snell, GHKRO, and PAPPA (显示 PAPPA 抗体)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (显示 MGMT 抗体)) and N-myc downstream-regulated gene 1 (NDRG1 (显示 NDRG1 抗体)).
STC2 (显示 STC2 抗体) is involved in regulating PAPP-A (显示 PAPPA 抗体) activity during the development of atherosclerosis
Study demonstrates proof-of-principle and provides feasibility for a novel therapeutic strategy to inhibit atherosclerotic plaque burden by selective targeting of PAPP-A (显示 PAPPA 抗体).
stimulation of PAPP-A (显示 PAPPA 抗体) expression by intermittent PTH (显示 PTH 抗体) treatment contributes to PTH (显示 PTH 抗体) bone anabolism in mice
PAPP-A (显示 PAPPA 抗体) affects fascicle structure, thereby affecting tendon phenotype.
This study demonstrated that cbp (显示 CREBBP 抗体) increase in skeletal muscle in muscle atrophy.
PAG is constitutively phosphorylated in resting T cells and rapidly dephosphorylated once the TCR is engaged.
The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation.
phosphoprotein associated with glycosphingolipid microdomains 1
, phosphoprotein associated with glycosphingolipid-enriched microdomains 1-like
, Csk-binding protein
, phosphoprotein associated with glycosphingolipid-enriched microdomains 1
, transmembrane adapter protein PAG
, transmembrane adaptor protein PAG
, transmembrane phosphoprotein Cbp
, Csk binding protein
, csk-binding protein
, phosphoprotein transmembrane adaptor 1
, phosphoprotein-associated with GEMs
, IGF-dependent IGFBP-4 protease
, insulin-like growth factor-dependent IGF-binding protein 4 protease