p53 产品
(Tumor Protein P53 (TP53))
Categories
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
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Featured p53 Categories
p53 抗体
High quality antibodies with extensive validation data.
p53 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
p53 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended p53 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (12)
Cat. No.
ABIN6256312
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP
Validations
- (5)
- (6)
Cat. No.
ABIN6149405
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), IP, ICC
Validations
- (1)
- (6)
Cat. No.
ABIN2854816
Quantity
100 μL
Datasheet
Datasheet
Recommended p53 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960305
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960306
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960307
Quantity
96 tests
Datasheet
Datasheet
Recommended p53 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (3)
- (1)
Cat. No.
ABIN1323380
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (3)
Cat. No.
ABIN2669713
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
- (2)
Cat. No.
ABIN2734068
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our p53 Products
: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).: "Tau affects P53 function and cell fate during the DNA damage response." in: Communications biology, Vol. 3, Issue 1, pp. 245, (2021) (PubMed).
: "Cynaropicrin Induces Cell Cycle Arrest and Apoptosis by Inhibiting PKM2 to Cause DNA Damage and Mitochondrial Fission in A549 Cells." in: Journal of agricultural and food chemistry, Vol. 69, Issue 45, pp. 13557-13567, (2021) (PubMed).
: "Garlic Extract Alleviates Trastuzumab-Induced Hepatotoxicity in Rats Through Its Antioxidant, Anti-Inflammatory, and Antihyperlipidemic Effects." in: Journal of inflammation research, Vol. 14, pp. 6305-6316, (2021) (PubMed).
: "UVB Irradiation Induced Cell Damage and Early Onset of Junbb Expression in Zebrafish." in: Animals : an open access journal from MDPI, Vol. 10, Issue 6, (2020) (PubMed).
: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).
: "Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes." in: Biochemical and biophysical research communications, Vol. 517, Issue 2, pp. 216-220, (2020) (PubMed).
: "Suitability of MDA, 8-OHdG and wild-type p53 as genotoxic biomarkers in metal (Co, Ni and Cr) exposed dental technicians: a cross-sectional study." in: BMC oral health, Vol. 20, Issue 1, pp. 65, (2020) (PubMed).
: "Discovery and characterization of a novel splice variant of the p53 tumor suppressor gene in a human T cell leukemia cellline." in: International journal of clinical and experimental pathology, Vol. 13, Issue 5, pp. 1121-1135, (2020) (PubMed).
: "Synergistic Action of 1,2-Epoxy-3 (3- (3,4-dimethoxyphenyl)- 4H-1-benzopiyran-4-on) Propane with Doxorubicin and Cisplatin through Increasing of p53, TIMP-3, and MicroRNA-34a in Cervical Cancer Cell ..." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 10, pp. 2955-2962, (2019) (PubMed).
Synonyms and alternative names related to p53
tumor protein p53 (TP53), cellular tumor antigen p53 (CpipJ_CPIJ002758), tumor protein p53 (Tp53), tumor protein p53 (tp53), transformation related protein 53 (Trp53), tumor protein p53 L homeolog (tp53.L), bbl, BCC7, bfy, bhy, brp53, drp53, etID22686.5, fb40d06, LFS1, p44, P53, p53, Tp53, tp53, TP53, TRP53, Trp53, wu:fb40d06, Xp53, zgc:111919Protein level used designations for p53
- antigen NY-CO-13
- cellular tumor antigen p53
- p53 tumor suppressor
- phosphoprotein p53
- transformation-related protein 53
- tumor suppressor p53
- transformation related protein 53
- tumor protein p53 (Li-Fraumeni syndrome)
- p53 tumor suppressor phosphoprotein
- tumor protein 53
- tumor suppressor protein
- p53 cellular tumor antigen
- tumor supressor p53
- Tumor suppressor p53
- Cellular tumor antigen p53
- Li-Fraumeni syndrome
- tumor suppressor protein p53
- P53
- tumor suppressing protein
- tumor suppressor ortholog
- tumor supressor protein
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