P4HA1 抗体
(Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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35 results
P4HA1
适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 马
WB
宿主: 兔
Polyclonal
unconjugated
1 image
P4HA1
适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 马, 兔, 豚鼠
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our P4HA1 抗体
: "In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes." in: BMC musculoskeletal disorders, Vol. 20, Issue 1, pp. 19, (2019) (PubMed).: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).
: "Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 2, pp. 151-64, (2014) (PubMed).
: "Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse." in: American journal of physiology. Heart and circulatory physiology, Vol. 307, Issue 5, pp. H773-81, (2014) (PubMed).
: "Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10819-29, (2013) (PubMed).
: "Collagen prolyl hydroxylases are essential for breast cancer metastasis." in: Cancer research, Vol. 73, Issue 11, pp. 3285-96, (2013) (PubMed).
: "BBF2H7-mediated Sec23A pathway is required for endoplasmic reticulum-to-Golgi trafficking in dermal fibroblasts to promote collagen synthesis." in: The Journal of investigative dermatology, Vol. 132, Issue 8, pp. 2010-8, (2012) (PubMed).
: "Proteomic changes in articular cartilage of human endemic osteoarthritis in China." in: Proteomics, Vol. 11, Issue 14, pp. 2881-90, (2011) (PubMed).
: "Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2." in: Molecular and cellular biology, Vol. 31, Issue 23, pp. 4760-74, (2011) (PubMed).
: "Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7067-78, (2010) (PubMed).
Aliases for P4HA1 抗体
prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ000975) 抗体prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ017131) 抗体
prolyl 4-hydroxylase subunit alpha-1 (Tsp_03346) 抗体
prolyl 4-hydroxylase subunit alpha-1 (Tsp_03347) 抗体
prolyl 4-hydroxylase subunit alpha-1 (Tsp_15957) 抗体
prolyl 4-hydroxylase subunit alpha 1 (P4HA1) 抗体
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide (P4ha1) 抗体
prolyl 4-hydroxylase subunit alpha 1 (P4ha1) 抗体
AL022634 抗体
P4HA 抗体
P4ha 抗体
PHalphaI 抗体
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