(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 5 (P2RX5))
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011].
Meng, Zheng, Yan, Li, Fang, Li: "P2X2 and P2X5 Receptors Mediate Bladder Hyperesthesia in ICC in Female Overactive Bladder." in: Cell biochemistry and biophysics, Vol. 72, Issue 2, pp. 375-83, (2016) (PubMed).
Abramowski, Ogrodowczyk, Martin, Pongs: "A truncation variant of the cation channel P2RX5 is upregulated during T cell activation." in: PLoS ONE, Vol. 9, Issue 9, pp. e104692, (2014) (PubMed).