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P-Selectin 产品

(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Categories

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008].

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Featured P-Selectin Categories

P-Selectin 抗体

High quality antibodies with extensive validation data.

P-Selectin ELISA试剂盒

Reliable ELISA kits for a wide range of species.

P-Selectin 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended P-Selectin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Pig, Rat
Application WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Validations
  • (4)
  • (5)
Cat. No. ABIN670131
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7441859
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7432088
Quantity 100 μL
Datasheet Datasheet

Recommended P-Selectin ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6959328
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959329
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6959331
Quantity 96 tests
Datasheet Datasheet

Recommended P-Selectin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275558
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275560
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320781
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our P-Selectin Products

Liu, Xiang, Gao, Yao, Ye, Wang: "The Inhibition of P-Selectin Reduced Severe Acute Lung Injury in Immunocompromised Mice." in: Oxidative medicine and cellular longevity, Vol. 2020, pp. 8430465, (2021) (PubMed).

Wang, Ma, Yin, Zhang, Luo, Pan, Wang: "Polycaprolactone vascular graft with epigallocatechin gallate embedded sandwiched layer-by-layer functionalization for enhanced antithrombogenicity and anti-inflammation." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 320, pp. 226-238, (2020) (PubMed).

Jing, Hu, Li, Wang, Si, Zheng, Liu, Liao, Liao, Bin: "Assessment of Thrombotic Risk in Atrial Fibrillation with Ultrasound Molecular Imaging of P-Selectin." in: Thrombosis and haemostasis, Vol. 118, Issue 2, pp. 388-400, (2019) (PubMed).

Borst, Münzer, Alnaggar, Geue, Tegtmeyer, Rath, Droppa, Seizer, Heitmeier, Heemskerk, Jennings, Storey, Angiolillo, Rocca, Spronk, Ten Cate, Gawaz, Geisler: "Inhibitory mechanisms of very low-dose rivaroxaban in non-ST-elevation myocardial infarction." in: Blood advances, Vol. 2, Issue 6, pp. 715-730, (2019) (PubMed).

Horioka, Tanaka, Isozaki, Okuda, Asari, Shiono, Ogawa, Shimizu: "Hypothermia-induced activation of the splenic platelet pool as a risk factor for thrombotic disease in a mouse model." in: Journal of thrombosis and haemostasis : JTH, (2019) (PubMed).

Yang, Jiang, Chen, He, Hu: "Protective effects of sinomenine against LPS-induced inflammation in piglets." in: Microbial pathogenesis, Vol. 110, pp. 573-577, (2018) (PubMed).

Stokol, Serpa, Brooks, Divers, Ness: "Subcutaneous Administration of Low-Molecular-Weight Heparin to Horses Inhibits Ex Vivo Equine Herpesvirus Type 1-Induced Platelet Activation." in: Frontiers in veterinary science, Vol. 5, pp. 106, (2018) (PubMed).

Xu, Gao, Fan, Yang: "Platelet membrane coating coupled with solar irradiation endows a photodynamic nanosystem with both improved antitumor efficacy and undetectable skin damage." in: Biomaterials, Vol. 159, pp. 59-67, (2018) (PubMed).

Fotiou, Sergentanis, Papageorgiou, Stamatelopoulos, Gavriatopoulou, Kastritis, Psaltopoulou, Salta, Van Dreden, Sangare, Larsen, Terpos, Elalamy, Dimopoulos, Gerotziafas et al.: "Longer procoagulant phospholipid-dependent clotting time, lower endogenous thrombin potential and higher tissue factor pathway inhibitor concentrations are associated with increased VTE occurrence in ..." in: Blood cancer journal, Vol. 8, Issue 11, pp. 102, (2018) (PubMed).

Serpa, Brooks, Divers, Ness, Birschmann, Papich, Stokol: "Pharmacokinetics and Pharmacodynamics of an Oral Formulation of Apixaban in Horses After Oral and Intravenous Administration." in: Frontiers in veterinary science, Vol. 5, pp. 304, (2018) (PubMed).

Synonyms and alternative names related to P-Selectin

selectin P (Selp), selectin P (SELP), selectin, platelet (Selp), CD62, CD62P, GMP-140, GMP140, GRMP, Grmp, LECAM3, PADGEM, PSEL, PSELECT

Protein level used designations for P-Selectin

  • CD62 antigen-like family member P
  • GMP-140
  • LECAM3
  • P-selectin
  • PADGEM
  • granule membrane protein 140
  • leukocyte-endothelial cell adhesion molecule 3
  • platelet activation dependent granule-external membrane protein
  • selectin, platelet
  • granulocyte membrane protein
  • platelet alpha-granule membrane protein
  • CD62P antigen
  • cell adhesion molecule
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