(Protein Associated with Topoisomerase II Homolog 1 (PATL1))
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly (By similarity).
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Aliases for PATL1 抗体
PAT1 homolog 1, processing body mRNA decay factor (PATL1) 抗体 protein associated with topoisomerase II homolog 1 L homeolog (patl1.L) 抗体 protein associated with topoisomerase II homolog 1 (yeast) (Patl1) 抗体 PAT1 homolog 1, processing body mRNA decay factor (Patl1) 抗体 protein associated with topoisomerase II homolog 1 (yeast) (patl1) 抗体 AV312086 抗体 D430024J04 抗体 fa11d04 抗体 hPat1b 抗体 Pat1b 抗体 RGD1305514 抗体 wu:fa11d04 抗体 xPat1b 抗体 zgc:158239 抗体