PARL Antibodies

This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Latest Publications for our PARL 抗体

Yoshioka, Katsu, Sakata, Okami, Wakai, Kinouchi, Chan: "The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 11, pp. 1658-65, (2013) (PubMed).

Chao, Parganas, Boyd, Hong, Opferman, Ihle: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).

Cipolat, Rudka, Hartmann, Costa, Serneels, Craessaerts, Metzger, Frezza, Annaert, DAdamio, Derks, Dejaegere, Pellegrini, DHooge, Scorrano, De Strooper: "Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling." in: Cell, Vol. 126, Issue 1, pp. 163-75, (2006) (PubMed).

Jeyaraju, Xu, Letellier, Bandaru, Zunino, Berg, McBride, Pellegrini: "Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18562-7, (2006) (PubMed).

McQuibban, Saurya, Freeman: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).

Pellegrini, Passer, Canelles, Lefterov, Ganjei, Fowlkes, Koonin, DAdamio: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).

Aliases for PARL 抗体

presenilin associated rhomboid like (PARL) 抗体
presenilin associated, rhomboid-like (Parl) 抗体
presenilin associated rhomboid like (Parl) 抗体
presenilin associated, rhomboid-like a (parla) 抗体
D16Ertd607e 抗体
parl 抗体
PRO2207 抗体
PSARL 抗体
Psarl 抗体
PSARL1 抗体
PSENIP2 抗体
RHBDS1 抗体
zgc:112986 抗体

PARL 抗体

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Latest Publications for our PARL 抗体

Aliases for PARL 抗体

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