PAK1 抗体
(P21-Activated Kinase 1 (PAK1))
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
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Latest Publications for our PAK1 抗体
: "The metastatic promoter DEPDC1B induces epithelial-mesenchymal transition and promotes prostate cancer cell proliferation via Rac1-PAK1 signaling." in: Clinical and translational medicine, Vol. 10, Issue 6, pp. e191, (2020) (PubMed).: "Effect of Th9/IL-9 on the growth of gastric cancer in nude mice." in: OncoTargets and therapy, Vol. 12, pp. 2225-2234, (2019) (PubMed).
: "p21-activated kinase 1 activity is required for histone H3 Ser10 phosphorylation and chromatin condensation in mouse oocyte meiosis." in: Reproduction, fertility, and development, Vol. 29, Issue 7, pp. 1287-1296, (2018) (PubMed).
: "Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice." in: Cell death and differentiation, Vol. 23, Issue 1, pp. 169-81, (2016) (PubMed).
: "Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer." in: Molecular cancer, Vol. 13, pp. 201, (2014) (PubMed).
: "SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic ? cells." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2527-34, (2013) (PubMed).
: "Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes." in: Journal of animal science and biotechnology, Vol. 4, Issue 1, pp. 13, (2013) (PubMed).
: "Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1709-22, (2013) (PubMed).
: "Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus." in: PLoS ONE, Vol. 6, Issue 10, pp. e26120, (2011) (PubMed).
: "Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease." in: Nature neuroscience, Vol. 9, Issue 2, pp. 234-42, (2006) (PubMed).
Aliases for PAK1 抗体
p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S) 抗体p21 (RAC1) activated kinase 1 (PAK1) 抗体
p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1) 抗体
p21 (RAC1) activated kinase 1 (Pak1) 抗体
Serine/threonine-protein kinase pak-1 (pak-1) 抗体
AW045634 抗体
pak 抗体
pak-1 抗体
PAK-1 抗体
Paka 抗体
pakalpha 抗体
PAKalpha 抗体
X-PAK1 抗体
XPak1 抗体
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