Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
Hosoi, Koguchi, Sugikawa, Chikada, Ogawa, Tsuda, Suto, Tsunoda, Taniguchi, Ohnuki: "Identification of a novel human eicosanoid receptor coupled to G(i/o)." in: The Journal of biological chemistry, Vol. 277, Issue 35, pp. 31459-65, (2002) (PubMed).