Orthodenticle Homeobox 2 抗体
(Orthodenticle Homeobox 2 (OTX2))
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012].
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58 results
OTX2
适用: 大鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
OTX2
适用: 大鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 488
OTX2
适用: 大鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
OTX2
适用: 人, 大鼠, 小鼠, 犬, 绵羊, 兔, 马, Cow, Bat, Hamster, Pig, 非洲爪蟾, 小鸡, Chimpanzee, Gibbon, 猴, Orang-Utan
WB
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our Orthodenticle Homeobox 2 抗体
: "Stem cells from human exfoliated deciduous tooth exhibit stromal-derived inducing activity and lead to generation of neural crest cells from human embryonic stem cells." in: Cell journal, Vol. 17, Issue 1, pp. 37-48, (2015) (PubMed).: "Endogenous regeneration of damaged retinal pigment epithelium following low dose sodium iodate administration: an insight into the role of glial cells in retinal repair." in: Experimental eye research, Vol. 112, pp. 68-78, (2013) (PubMed).
: "OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas." in: Cancer research, Vol. 70, Issue 1, pp. 181-91, (2010) (PubMed).
: "SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 35, pp. 26933-44, (2010) (PubMed).
: "The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons." in: Brain : a journal of neurology, Vol. 133, Issue Pt 7, pp. 2022-31, (2010) (PubMed).
: "A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency." in: Human genetics, Vol. 127, Issue 6, pp. 721-9, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases." in: The British journal of ophthalmology, Vol. 94, Issue 8, pp. 1100-4, (2010) (PubMed).
: "Differential CRX and OTX2 expression in human retina and retinoblastoma." in: Journal of neurochemistry, Vol. 111, Issue 1, pp. 250-63, (2009) (PubMed).
: "Novel heterozygous OTX2 mutations and whole gene deletions in anophthalmia, microphthalmia and coloboma." in: Human mutation, Vol. 29, Issue 11, pp. E278-83, (2008) (PubMed).
Aliases for Orthodenticle Homeobox 2 抗体
orthodenticle homeobox 2 (OTX2) 抗体orthodenticle homeobox 2 (Otx2) 抗体
orthodenticle homeobox 2 (otx2) 抗体
orthodenticle homeobox 2 S homeolog (otx2.S) 抗体
orthodenticle homeobox 2 L homeolog (otx2.L) 抗体
CPHD6 抗体
E130306E05Rik 抗体
id:ibd2915 抗体
MCOPS5 抗体
otx-2 抗体
otx2 抗体
Xotx-2 抗体
Xotx2 抗体
zgc:136535 抗体
zotx-2 抗体
zOtx2 抗体
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