This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010].
Storey, McIntosh, Huang, Landrock, Martin, Landrock, Payne, Atshaves, Kier, Schroeder: "Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 8, pp. G824-39, (2012) (PubMed).
Higashimoto, Soejima, Yatsuki, Joh, Uchiyama, Obata, Ono, Wang, Xin, Zhu, Masuko, Ishino, Hatada, Jinno, Iwasaka, Katsuki, Mukai: "Characterization and imprinting status of OBPH1/Obph1 gene: implications for an extended imprinting domain in human and mouse." in: Genomics, Vol. 80, Issue 6, pp. 575-84, (2002) (PubMed).
Aliases for OSBPL5 抗体
oxysterol binding protein-like 5 (Osbpl5) 抗体 oxysterol binding protein like 5 (OSBPL5) 抗体 oxysterol binding protein like 5 (osbpl5) 抗体 1110006M06Rik 抗体 AI462538 抗体 MGC109308 抗体 OBPH1 抗体 Obph1 抗体 ORP5 抗体 Osbp2 抗体 OSBPL5 抗体