OGT 产品
(O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))
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This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Featured OGT Categories
OGT 抗体
High quality antibodies with extensive validation data.
OGT ELISA试剂盒
Reliable ELISA kits for a wide range of species.
OGT 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OGT 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, IF, FACS
Validations
- (6)
Cat. No.
ABIN190863
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN3022708
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), IP, ICC, FACS
Validations
- (8)
Cat. No.
ABIN2856718
Quantity
100 μL
Datasheet
Datasheet
Recommended OGT ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958285
Quantity
96 tests
Datasheet
Datasheet
Recommended OGT 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313359
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3094291
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3136462
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our OGT Products
: "Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation." in: The Journal of biological chemistry, Vol. 291, Issue 25, pp. 12917-29, (2016) (PubMed).: "Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33927-38, (2013) (PubMed).
: "Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin." in: Glycobiology, Vol. 22, Issue 6, pp. 788-805, (2012) (PubMed).
: "Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-?B acetylation and transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 42, pp. 16888-93, (2012) (PubMed).
: "Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase." in: The Journal of biological chemistry, Vol. 283, Issue 10, pp. 6050-7, (2008) (PubMed).
: "Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1." in: Diabetes, Vol. 53, Issue 12, pp. 3184-92, (2004) (PubMed).
Synonyms and alternative names related to OGT
O-linked N-acetylglucosamine (GlcNAc) transferase L homeolog (ogt.L), super sex combs (sxc), O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 (ogt.1), O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), O-linked N-acetylglucosamine (GlcNAc) transferase (ogt), O-linked GlcNAc transferase (GL50803_12081), O-linked GlcNAc transferase (GL50803_41701), o-linked GlcNAc transferase (THAPSDRAFT_264441), O-linked GlcNAc transferase (spyA), O-linked N-acetylglucosamine (GlcNAc) transferase (Ogt), O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (Ogt), 1110038P24Rik, 4831420N21Rik, AI115525, BcDNA:GH04245, CG10392, Dmel\\CG10392, fm81g08, HRNT1, l(2)02637, l(2)NC130, O-GLCNAC, OGT, Ogt, ogt, Ogtl, P1201, SXC, Sxc, sxc/Ogt, wu:fc12b01, wu:fm81g08Protein level used designations for OGT
- O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
- O-linked GlcNAc transferase
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase
- CG10392-PA
- CG10392-PB
- CG10392-PC
- O-glycosyltransferase
- O-linked N-acetylglucosamine transferase
- lethal (2) NC130
- sxc-PA
- sxc-PB
- sxc-PC
- O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1
- copy I
- ogta
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- o-linked GlcNAc transferase
- TPR repeat-containing protein
- UDP-N-acetylglucosamine:peptide N-acetylglucosaminyltransferase
- O linked N-acetylglucosamine transferase
- O-GlcNAc transferase subunit p110
- O-linked N-acetylglucosamine transferase 110 kDa subunit
- UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase
- O-GlcNAc transferase p110 subunit
- uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
- O linked N-acetylglucosamine transferase like
- UDP-N-acetylglucosaminyltransferase
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