NXT1 产品
(NTF2-Related Export Protein 1 (NXT1))
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The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008].
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Recommended NXT1 蛋白
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Latest Publications for our NXT1 Products
: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, (2008) (PubMed).: "Influenza virus targets the mRNA export machinery and the nuclear pore complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 6, pp. 1853-8, (2007) (PubMed).
: "An efficient protein complex purification method for functional proteomics in higher eukaryotes." in: Nature biotechnology, Vol. 21, Issue 1, pp. 89-92, (2003) (PubMed).
: "Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9242-6, (2002) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
: "Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes." in: Molecular and cellular biology, Vol. 22, Issue 1, pp. 245-56, (2001) (PubMed).
Synonyms and alternative names related to NXT1
NTF2-related export protein 1 (Nxt1), NTF2-related export protein (LOC413378), NTF2-related export protein 1 (Tsp_05214), nuclear transport factor 2 like export factor 1 (NXT1), nuclear transport factor 2-like export factor 1 (Nxt1), 1110001N02Rik, CG12752, Dmel\\CG12752, dmNXT, DmNXT1, dmNXT1, dmP15, dNxt, GB14514, MTR2, Nxt, nxt1, p15, P15Protein level used designations for NXT1
- CG12752-PA
- Nxt1-PA
- NTF2-related export protein 1
- NTX2-like export factor1
- NUTF-like export factor 1
- protein p15
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