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NXT1 抗体 (C-Term)

NXT1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB30598 unconjugated
产品编号 ABIN1881591
发货至: 中国
  • 抗原 See all NXT1 抗体
    NXT1 (NTF2-Related Export Protein 1 (NXT1))
    抗原表位
    • 13
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 85-111, C-Term
    适用
    • 15
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 17
    • 5
    克隆类型
    • 20
    • 2
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This NXT1 antibody is un-conjugated
    应用范围
    • 22
    • 15
    • 3
    • 1
    Western Blotting (WB)
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This NXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the C-terminal region of human NXT1.
    克隆位点
    RB30598
    亚型
    Ig Fraction
    Top Product
    Discover our top product NXT1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Venkatesan, Rual, Vazquez, Stelzl, Lemmens, Hirozane-Kishikawa, Hao, Zenkner, Xin, Goh, Yildirim, Simonis, Heinzmann, Gebreab, Sahalie, Cevik, Simon, de Smet, Dann, Smolyar, Vinayagam, Yu et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, (2008) (PubMed).

    Forler, Köcher, Rode, Gentzel, Izaurralde, Wilm: "An efficient protein complex purification method for functional proteomics in higher eukaryotes." in: Nature biotechnology, Vol. 21, Issue 1, pp. 89-92, (2003) (PubMed).

    Katahira, Straesser, Saiwaki, Yoneda, Hurt: "Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9242-6, (2002) (PubMed).

    Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

    Wiegand, Coburn, Zeng, Kang, Bogerd, Cullen: "Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes." in: Molecular and cellular biology, Vol. 22, Issue 1, pp. 245-56, (2001) (PubMed).

  • 抗原
    NXT1 (NTF2-Related Export Protein 1 (NXT1))
    别名
    NXT1 (NXT1 产品)
    别名
    CG12752 antibody, DmNXT1 antibody, Dmel\\CG12752 antibody, Nxt antibody, dNxt antibody, dmNXT antibody, dmNXT1 antibody, dmP15 antibody, nxt1 antibody, p15 antibody, GB14514 antibody, MTR2 antibody, P15 antibody, 1110001N02Rik antibody, NTF2-related export protein 1 antibody, NTF2-related export protein antibody, nuclear transport factor 2 like export factor 1 antibody, nuclear transport factor 2-like export factor 1 antibody, Nxt1 antibody, LOC413378 antibody, Tsp_05214 antibody, NXT1 antibody
    背景
    The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
    NCBI登录号
    NP_037380
    UniProt
    Q9UKK6
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