NUP98 抗体
(Nucleoporin 98kDa (NUP98))
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, May 2010].
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58 results
NUP98
适用: 人
WB, ELISA, IP, IF
宿主: 兔
Polyclonal
unconjugated
NUP98
适用: 人
WB, ELISA, IF, IHC
宿主: 兔
Monoclonal
2H4
unconjugated
Recombinant Antibody
NUP98
适用: 人, 大鼠, 马, 兔, Cow, 猴
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
1 image
NUP98
适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 猴, 斑马鱼, Bat
WB
宿主: 兔
Polyclonal
unconjugated
1 image
NUP98
适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 小鸡, 非洲爪蟾
WB, IF
宿主: 兔
Polyclonal
unconjugated
1 image
NUP98
适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, Saccharomyces cerevisiae, 斑马鱼
WB, IF
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our NUP98 抗体
: "NPHP proteins are binding partners of nucleoporins at the base of the primary cilium." in: PLoS ONE, Vol. 14, Issue 9, pp. e0222924, (2019) (PubMed).: "Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia." in: Nature, Vol. 561, Issue 7721, pp. 127-131, (2018) (PubMed).
: "Tpr regulates the total number of nuclear pore complexes per cell nucleus." in: Genes & development, Vol. 32, Issue 19-20, pp. 1321-1331, (2018) (PubMed).
: "Evolution of a transcriptional regulator from a transmembrane nucleoporin." in: Genes & development, Vol. 30, Issue 10, pp. 1155-71, (2016) (PubMed).
: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
: "Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 7, pp. 661-9, (2010) (PubMed).
: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." in: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).
Aliases for NUP98 抗体
Nucleoporin 98-96kD (Nup98-96) 抗体nuclear pore complex protein Nup98-Nup96 (LOC408335) 抗体
nucleoporin 98 (NUP98) 抗体
nuclear pore complex protein Nup98-Nup96 (LOC587580) 抗体
nucleoporin 98kDa (NUP98) 抗体
nucleoporin 98 (Nup98) 抗体
nucleoporin 98 (nup98) 抗体
nucleoporin 98 L homeolog (nup98.L) 抗体
4732457F17 抗体
ADIR2 抗体
AI849286 抗体
CG10198 抗体
CG10201 抗体
Dmel\\CG10198 抗体
GB12688 抗体
im:7151238 抗体
l(3)95BCd 抗体
Nup-98 抗体
Nup 96 抗体
Nup96 抗体
NUP96 抗体
Nup 98 抗体
Nup98 抗体
NUP98 抗体
nup98-96 抗体
Nup98-Nup96 抗体
Nup98/96 抗体
nup145 抗体
NUP196 抗体
zgc:63593 抗体
zgc:113968 抗体
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