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Niemann-Pick Disease, Type C1 蛋白

(Niemann-Pick Disease, Type C1 (NPC1))
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
NPC1 Protein (AA 151-250) (GST tag) NPC1 Protein (AA 151-250) (GST tag) NPC1 Protein (AA 151-250) (GST tag) (ABIN1312849)

NPC1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

NPC1 Protein (His tag,DYKDDDDK Tag) NPC1 Protein (His tag,DYKDDDDK Tag) NPC1 Protein (His tag,DYKDDDDK Tag) (ABIN7317151)

NPC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.

NPC1 Protein (His tag) (ABIN7578508)

NPC1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, ELISA, SDS

Niemann-Pick Disease, Type C1 蛋白 by Origin

Find Niemann-Pick Disease, Type C1 蛋白 for a variety of species such as anti-Human Niemann-Pick Disease, Type C1, anti-Mouse Niemann-Pick Disease, Type C1, anti-Rat Niemann-Pick Disease, Type C1. The species listed below are among those available. Click on a link to go to the corresponding products.

Niemann-Pick Disease, Type C1 蛋白 by Source

Here you will find Niemann-Pick Disease, Type C1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Niemann-Pick Disease, Type C1 蛋白 by 蛋白类型

Here you can find Niemann-Pick Disease, Type C1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Niemann-Pick Disease, Type C1 蛋白 by 应用范围

Find Niemann-Pick Disease, Type C1 蛋白 validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Niemann-Pick Disease, Type C1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312849
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7317151
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7578508
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7578507
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
Cat. No. ABIN7578506
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750647
Quantity 5 applications
Datasheet Datasheet

Aliases for Niemann-Pick Disease, Type C1 蛋白

NPC intracellular cholesterol transporter 1 (NPC1) 蛋白
NPC1 like intracellular cholesterol transporter 1 (Npc1l1) 蛋白
NPC intracellular cholesterol transporter 1 (Npc1) 蛋白
Niemann-Pick disease, type C1 (npc1) 蛋白
Niemann-Pick C1 protein (LOC579887) 蛋白
9130221N23Rik 蛋白
A430089E03Rik 蛋白
C85354 蛋白
Cdig2 蛋白
D18Ertd139e 蛋白
D18Ertd723e 蛋白
Gm243 蛋白
im:7149020 蛋白
lcsd 蛋白
nmf164 蛋白
NPC 蛋白
spm 蛋白
wu:fb53a12 蛋白
wu:fc29a12 蛋白
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