NOXA 蛋白
(Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
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PMAIP1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for NOXA 蛋白
phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) 蛋白phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1) 蛋白
phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) 蛋白
APR 蛋白
NOXA 蛋白
Noxa 蛋白
PMAIP1 蛋白
TN3 蛋白
zgc:162379 蛋白
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