Notch1 抗体
(Notch 1 (NOTCH1))
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant Notch1 抗体 | 人 | 兔 Monoclonal |
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| Notch1 抗体 (AA 2505-2555) | 人 | 兔 Polyclonal |
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| Notch1 抗体 | 人, 小鼠 | 小鼠 Monoclonal |
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| Notch1 抗体 (cleaved, Val1754) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Notch1 抗体 (AA 23-132) | 人 | 小鼠 Monoclonal |
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| Notch1 抗体 (AA 171-182) | 人 | 山羊 Polyclonal |
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| Notch1 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| Notch1 抗体 (C-Term) | 小鼠 | 兔 Polyclonal |
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| Notch1 抗体 (AA 2505-2555) | 人 | 兔 Polyclonal |
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| Notch1 抗体 (FITC) | 人, 小鼠 | 小鼠 Monoclonal |
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| Notch1 抗体 (PE) | 人, 小鼠 | 小鼠 Monoclonal |
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| Notch1 抗体 (C-Term) | 人, 小鼠, 大鼠, Cow, 犬, 猴 | 兔 Polyclonal |
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| Notch1 抗体 (AA 1755-1767) | 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, Tetraodontidae (Puffer Fish) | 兔 Polyclonal |
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| Notch1 抗体 (Middle Region) | 人, 小鼠, 大鼠, 斑马鱼, 小鸡, 非洲爪蟾 | 兔 Polyclonal |
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| Recombinant Notch1 抗体 | 人, 小鼠 | 兔 Chimeric |
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| Notch1 抗体 | 小鼠 | 大鼠 Monoclonal |
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| Notch1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| Notch1 抗体 (Center) | 人, 小鼠 | 兔 Polyclonal |
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| Notch1 抗体 (Middle Region) | 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马 | 兔 Polyclonal |
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| Notch1 抗体 (AA 2101-2300) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 4F6
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2505-2555
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
4 references - 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- mN1A
- 标记
- unconjugated
- 抗体亚型
- IgG1, kappa
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Val1754, cleaved
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4G1
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 23-132
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 171-182
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB51626
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 2428-2462, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB51208
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 2403-2437, C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2505-2555
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- mN1A
- 标记
- FITC
- 抗体亚型
- IgG1
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- mN1A
- 标记
- PE
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 斑马鱼, 小鸡, 非洲爪蟾
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Chimeric
- 克隆
- E6
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, lambda
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 2101-2300
Latest Publications for our Notch1 抗体
: "Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway." in: Scientific reports, Vol. 10, Issue 1, pp. 5708, (2020) (PubMed).
: "Enhanced lysosomal degradation maintains the quiescent state of neural stem cells." in: Nature communications, Vol. 10, Issue 1, pp. 5446, (2019) (PubMed).
: "Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling." in: Cell stem cell, Vol. 23, Issue 4, pp. 530-543.e9, (2018) (PubMed).
: "Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations." in: Scientific reports, Vol. 8, Issue 1, pp. 17987, (2018) (PubMed).
: "Prognostic implication of NOTCH1 in early stage oral squamous cell cancer with occult metastases." in: Clinical oral investigations, (2017) (PubMed).
: "NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 4, pp. 1106-1119, (2017) (PubMed).
: "Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning." in: Developmental cell, Vol. 40, Issue 5, pp. 505-511.e6, (2017) (PubMed).
: "Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1." in: The Journal of biological chemistry, Vol. 292, Issue 2, pp. 732-747, (2017) (PubMed).
: "Chlamydia and ocular adnexal lymphomas: An Indian experience." in: Experimental and molecular pathology, Vol. 101, Issue 1, pp. 74-80, (2016) (PubMed).
: "Growth inhibitory effect of rapamycin in Hodgkin-lymphoma cell lines characterized by constitutive NOTCH1 activation." in: Tumour biology, Vol. 37, Issue 10, pp. 13695-13704, (2016) (PubMed).
: "Enhanced lysosomal degradation maintains the quiescent state of neural stem cells." in: Nature communications, Vol. 10, Issue 1, pp. 5446, (2019) (PubMed).
: "Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling." in: Cell stem cell, Vol. 23, Issue 4, pp. 530-543.e9, (2018) (PubMed).
: "Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations." in: Scientific reports, Vol. 8, Issue 1, pp. 17987, (2018) (PubMed).
: "Prognostic implication of NOTCH1 in early stage oral squamous cell cancer with occult metastases." in: Clinical oral investigations, (2017) (PubMed).
: "NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 4, pp. 1106-1119, (2017) (PubMed).
: "Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning." in: Developmental cell, Vol. 40, Issue 5, pp. 505-511.e6, (2017) (PubMed).
: "Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1." in: The Journal of biological chemistry, Vol. 292, Issue 2, pp. 732-747, (2017) (PubMed).
: "Chlamydia and ocular adnexal lymphomas: An Indian experience." in: Experimental and molecular pathology, Vol. 101, Issue 1, pp. 74-80, (2016) (PubMed).
: "Growth inhibitory effect of rapamycin in Hodgkin-lymphoma cell lines characterized by constitutive NOTCH1 activation." in: Tumour biology, Vol. 37, Issue 10, pp. 13695-13704, (2016) (PubMed).
Aliases for Notch1 抗体
notch 1 (notch1) 抗体fibropellin-1 (LOC100631526) 抗体
Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) 抗体
notch 1 (NOTCH1) 抗体
Notch homolog 1, translocation-associated (NOTCH1) 抗体
notch 1 (Notch1) 抗体
notch 1 S homeolog (notch1.S) 抗体
9930111A19Rik 抗体
hn1 抗体
hN1 抗体
lin-12 抗体
Mis6 抗体
N1 抗体
notch 抗体
NOTCH 抗体
notch-1 抗体
notch1 抗体
NOTCH1 抗体
notch1-a 抗体
tan1 抗体
TAN1 抗体
Tan1 抗体
xnotch 抗体
xnotch1 抗体
xotch 抗体
Xotch 抗体
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