NOD2 抗体
(Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008].
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Latest Publications for our NOD2 抗体
: "Nicotine modulates molecules of the innate immune response in epithelial cells and macrophages during infection with M. tuberculosis." in: Clinical and experimental immunology, Vol. 199, Issue 2, pp. 230-243, (2020) (PubMed).: "The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 48, Issue 1, pp. 87-95, (2019) (PubMed).
: "Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation." in: Glia, Vol. 66, Issue 11, pp. 2427-2437, (2019) (PubMed).
: "NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular ..." in: Journal of cancer research and clinical oncology, Vol. 145, Issue 6, pp. 1405-1416, (2019) (PubMed).
: "Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2. ..." in: Cold Spring Harbor molecular case studies, Vol. 5, Issue 1, (2019) (PubMed).
: "Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils." in: Journal of innate immunity, (2017) (PubMed).
: "Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication." in: PLoS ONE, Vol. 9, Issue 3, pp. e92704, (2014) (PubMed).
: "NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells." in: Inflammatory bowel diseases, Vol. 20, Issue 1, pp. 126-35, (2013) (PubMed).
: "NOD1 and NOD2 regulate proinflammatory and prolabor mediators in human fetal membranes and myometrium via nuclear factor-kappa B." in: Biology of reproduction, Vol. 89, Issue 1, pp. 14, (2013) (PubMed).
: "RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 52, pp. 21426-31, (2012) (PubMed).
Aliases for NOD2 抗体
caspase recruitment domain 15 protein (TTHERM_01951320) 抗体nucleotide binding oligomerization domain containing 2 (NOD2) 抗体
nucleotide-binding oligomerization domain containing 2 (Nod2) 抗体
ACUG 抗体
BLAU 抗体
CARD15 抗体
Card15 抗体
CD 抗体
CLR16.3 抗体
F830032C23Rik 抗体
IBD1 抗体
NLRC2 抗体
Nlrc2 抗体
NOD2B 抗体
PSORAS1 抗体
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