NLRP1 抗体
(NLR Family, Pyrin Domain Containing 1 (NLRP1))
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
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Latest Publications for our NLRP1 抗体
: "Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 292, (2019) (PubMed).: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination." in: Metabolic brain disease, (2019) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." in: Journal of biophotonics, (2017) (PubMed).
: "NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model." in: Journal of neuroinflammation, Vol. 12, pp. 18, (2015) (PubMed).
: "Intermittent fasting attenuates inflammasome activity in ischemic stroke." in: Experimental neurology, Vol. 257, pp. 114-9, (2014) (PubMed).
: "Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke." in: Cell death & disease, Vol. 4, pp. e790, (2013) (PubMed).
: "Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 3, pp. 806-14.e1-4, (2011) (PubMed).
: "Inflammasome mRNA expression in human monocytes during early septic shock." in: American journal of respiratory and critical care medicine, Vol. 177, Issue 9, pp. 983-8, (2008) (PubMed).
: "Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 55, Issue 5, pp. 443-52, (2007) (PubMed).
Aliases for NLRP1 抗体
NLR family pyrin domain containing 1 (NLRP1) 抗体NLR family pyrin domain containing 1 (Nlrp1) 抗体
CARD7 抗体
CIDED 抗体
CLR17.1 抗体
DEFCAP 抗体
DEFCAP-L/S 抗体
NAC 抗体
NALP1 抗体
PP1044 抗体
SLEV1 抗体
VAMAS1 抗体
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