(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Zhu, Li, Yang, Tian, Wang, Yuan, Dong, He, Wang, Li: "Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation." in: Scientific reports, Vol. 6, pp. 19069, (2016) (PubMed).
Zheng, Turton, Zhu, Li, Grindle, Annis, Lu, Drennan, Tweardy, Bharadwaj, Mosher, Rui: "A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture." in: Oncogenesis, Vol. 4, pp. e184, (2016) (PubMed).
Aliases for NFKBIZ 抗体
NFKB inhibitor zeta (Nfkbiz) 抗体 NFKB inhibitor zeta (NFKBIZ) 抗体 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (nfkbiz) 抗体 NFKB inhibitor zeta (nfkbiz) 抗体 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta (Nfkbiz) 抗体 AA408868 抗体 IKBZ 抗体 INAP 抗体 MAIL 抗体 Mail 抗体 NFKBIZ 抗体 RGD1310834 抗体