Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq, Aug 2008].
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Aliases for PFKL 抗体
phosphofructokinase, liver type (PFKL) 抗体 phosphofructokinase, liver type (Pfkl) 抗体 phosphofructokinase, liver, B-type (Pfkl) 抗体 AA407869 抗体 PFK-B 抗体