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Nephrin 抗体

(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009].

Active filters:

  • 抗原: Nephrin (NPHS1)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN2320979
Nephrin 抗体 (AA 23-1029) NPHS1 · Primary Antibody 人 绵羊 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IC (Immunochromatography: 所列应用)
  • 100 μg
发货至: 中国
ABIN1453620
Nephrin 抗体 (AA 843-892) NPHS1 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • 100 μL
  • 20 μg
  • 50 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IC (Immunochromatography: 所列应用)
适用
人
宿主
绵羊
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 23-1029
产品编号 ABIN2320979
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IF (Immunofluorescence: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 843-892
产品编号 ABIN1453620
100 μL (More quantities available)
发货至: 中国
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Latest Publications for our Nephrin 抗体

Wang, Feng, He, Sun, He, Jin: "miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury." in: Bioengineered, (2021) (PubMed).

Zhou, Chen, Lu, Wu, Yuan, Hu, Miao, Zhang, Li, Hou, Nie, Liu: "Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria." in: Kidney international, Vol. 95, Issue 4, pp. 830-845, (2020) (PubMed).

Wang, Gao, Tian, Wang, Shi, Xu, Wu: "Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT-NF-κB p65 axis." in: Scientific reports, Vol. 9, Issue 1, pp. 323, (2019) (PubMed).

Chen, Cheng, Chen, Shao, Sung, Chiang, Yang, Lin, Sun, Sheu, Chang, Lee, Yip: "Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats." in: Oncotarget, Vol. 8, Issue 59, pp. 100002-100020, (2018) (PubMed).

Estrada, Paladugu, Guo, Pace, Revelo, Salant, Shankland, DAgati, Mehrotra, Cardona, Bialkowska, Yang, He, Mallipattu: "Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation." in: JCI insight, Vol. 3, Issue 12, (2018) (PubMed).

Wang, Gao, Tian, Zou, Shi, Zhang: "Astragaloside IV improves renal function and fibrosis via inhibition of miR-21-induced podocyte dedifferentiation and mesangial cell activation in diabetic mice." in: Drug design, development and therapy, Vol. 12, pp. 2431-2442, (2018) (PubMed).

Eng, Kaverina, Schneider, Freedman, Gross, Miner, Pippin, Shankland: "Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing." in: Kidney international, Vol. 93, Issue 5, pp. 1240-1246, (2018) (PubMed).

de Groot, Damen, Kosse, Alsady, Doty, Baumgarten, Sheehan, van der Vlag, Korstanje, Deen: "Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice." in: PLoS ONE, Vol. 12, Issue 12, pp. e0189485, (2018) (PubMed).

Hu, Azeloglu, Ron, Tran-Ba, Calizo, Tavassoly, Bhattacharya, Jayaraman, Chen, Rabinovich, Iyengar, Hone, He, Kaufman: "A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction." in: Scientific reports, Vol. 7, pp. 43934, (2017) (PubMed).

Fu, Guo, Wang, Huang, Jin, Hu, Chen, Xu, Zhou, Zhao, Sung, Wang, Gaskin, Yang, Fu: "Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 69, Issue 8, pp. 1636-1646, (2017) (PubMed).

Aliases for Nephrin 抗体

NPHS1, nephrin (NPHS1) 抗体
nephrosis 1, congenital, Finnish type (nephrin) (nphs1) 抗体
NPHS1 nephrin S homeolog (nphs1.S) 抗体
nephrin (LOC5579127) 抗体
NPHS1 nephrin (Nphs1) 抗体
NPHS1, nephrin (Nphs1) 抗体
nephrosis 1, nephrin (Nphs1) 抗体
CNF 抗体
nephrin 抗体
NephrinB 抗体
NPHN 抗体
NPHS1 抗体
nphs1 抗体
nphs1l 抗体
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