Nephrin 抗体
(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009].
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Latest Publications for our Nephrin 抗体
: "miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury." in: Bioengineered, (2021) (PubMed).: "Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria." in: Kidney international, Vol. 95, Issue 4, pp. 830-845, (2020) (PubMed).
: "Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT-NF-κB p65 axis." in: Scientific reports, Vol. 9, Issue 1, pp. 323, (2019) (PubMed).
: "Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats." in: Oncotarget, Vol. 8, Issue 59, pp. 100002-100020, (2018) (PubMed).
: "Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation." in: JCI insight, Vol. 3, Issue 12, (2018) (PubMed).
: "Astragaloside IV improves renal function and fibrosis via inhibition of miR-21-induced podocyte dedifferentiation and mesangial cell activation in diabetic mice." in: Drug design, development and therapy, Vol. 12, pp. 2431-2442, (2018) (PubMed).
: "Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing." in: Kidney international, Vol. 93, Issue 5, pp. 1240-1246, (2018) (PubMed).
: "Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice." in: PLoS ONE, Vol. 12, Issue 12, pp. e0189485, (2018) (PubMed).
: "A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction." in: Scientific reports, Vol. 7, pp. 43934, (2017) (PubMed).
: "Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 69, Issue 8, pp. 1636-1646, (2017) (PubMed).
Aliases for Nephrin 抗体
NPHS1, nephrin (NPHS1) 抗体nephrosis 1, congenital, Finnish type (nephrin) (nphs1) 抗体
NPHS1 nephrin S homeolog (nphs1.S) 抗体
nephrin (LOC5579127) 抗体
NPHS1 nephrin (Nphs1) 抗体
NPHS1, nephrin (Nphs1) 抗体
nephrosis 1, nephrin (Nphs1) 抗体
CNF 抗体
nephrin 抗体
NephrinB 抗体
NPHN 抗体
NPHS1 抗体
nphs1 抗体
nphs1l 抗体
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