This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Tarry-Adkins, Fernandez-Twinn, Chen, Hargreaves, Martin-Gronert, McConnell, Ozanne: "Nutritional programming of coenzyme Q: potential for prevention and intervention?" in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 12, pp. 5398-405, (2014) (PubMed).
Hazra, Izumi, Boldogh, Imhoff, Kow, Jaruga, Dizdaroglu, Mitra: "Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 6, pp. 3523-8, (2002) (PubMed).
Aliases for NEIL1 抗体
nei-like DNA glycosylase 1 (Neil1) 抗体 nei like DNA glycosylase 1 (NEIL1) 抗体 nei endonuclease VIII-like 1 (E. coli) (Neil1) 抗体 2810450N13Rik 抗体 FPG1 抗体 hFPG1 抗体 NEI1 抗体 Nei1 抗体