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NEDD4 抗体

(Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Involved in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19193720). Predominantly involved in ubiquitination of membrane bound forms of ERBB4 rather than processed precursors and intermediate membrane-anchored 80 kDa fragments (m80HER4), with a lesser role in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19047365). Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2 (By similarity).
NEDD4 抗体  (AA 1288-1319) NEDD4 抗体  (AA 1288-1319) NEDD4 抗体 (AA 1288-1319) (ABIN3031966)

NEDD4 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

NEDD4 抗体  (AA 160-460) NEDD4 抗体  (AA 160-460) NEDD4 抗体 (AA 160-460) (ABIN1681009)

NEDD4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

NEDD4 抗体  (AA 801-900) NEDD4 抗体  (AA 801-900) NEDD4 抗体 (AA 801-900) (ABIN872620)

NEDD4 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

NEDD4 抗体 by 适用

Find NEDD4 抗体 for a variety of species such as anti-Human NEDD4, anti-Rat NEDD4, anti-Mouse NEDD4. The species listed below are among those available. Click on a link to go to the corresponding products.

NEDD4 抗体 by 应用范围

Find NEDD4 抗体 validated for a specific application such as WB, FACS, ELISA, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

NEDD4 抗体 by 抗体来源

Find NEDD4 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

NEDD4 抗体 by 抗原表位

Find NEDD4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NEDD4 抗体 by 克隆形成能力

Find available monoclonal or polyclonal NEDD4 抗体. Click on a link to go to the corresponding products.

NEDD4 抗体 by 克隆

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NEDD4 抗体 by 标记

Find NEDD4 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 350. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NEDD4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN3031966
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN1681009
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (2)
Cat. No. ABIN872620
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (2)
Cat. No. ABIN7254929
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN653889
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, FACS
Validations
  • (3)
Cat. No. ABIN2971025
Quantity 400 μL
Datasheet Datasheet
Reactivity Horse, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN960275
Quantity 100 μg
Datasheet Datasheet
Reactivity Horse, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN960274
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Horse, Human, Monkey, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6743150
Quantity 100 μL
Datasheet Datasheet
Reactivity Horse, Human, Macaque
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN349606
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2774920
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN916374
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN916363
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN916364
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN916365
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our NEDD4 抗体

Zhang, Li, Rezaeian, Xu, Chou, Jin, Han, Pan, Wang, Long, Zhang, Huang, Tsai, Tsai, Logothetis, Lin: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." in: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).

Peruzzi, Prisco, Morrione, Valentinis, Baserga: "Anti-apoptotic signaling of the insulin-like growth factor-I receptor through mitochondrial translocation of c-Raf and Nedd4." in: The Journal of biological chemistry, Vol. 276, Issue 28, pp. 25990-6, (2001) (PubMed).

Harvey, Dinudom, Komwatana, Jolliffe, Day, Parasivam, Cook, Kumar: "All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+." in: The Journal of biological chemistry, Vol. 274, Issue 18, pp. 12525-30, (1999) (PubMed).

Plant, Yeger, Staub, Howard, Rotin: "The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32329-36, (1998) (PubMed).

Hatakeyama, Jensen, Weissman: "Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases." in: The Journal of biological chemistry, Vol. 272, Issue 24, pp. 15085-92, (1997) (PubMed).

Aliases for NEDD4 抗体

neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (NEDD4) 抗体
neural precursor cell expressed, developmentally down-regulated 4 (Nedd4) 抗体
CG42279 gene product from transcript CG42279-RJ (Nedd4) 抗体
E3 ubiquitin-protein ligase Nedd-4 (LOC411723) 抗体
E3 ubiquitin-protein ligase NEDD4 (LOC100457150) 抗体
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (nedd4) 抗体
E3 ubiquitin-protein ligase NEDD4 (LOC100547485) 抗体
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (Nedd4) 抗体
AA959633 抗体
AL023035 抗体
AU019897 抗体
CG7555 抗体
CG32184 抗体
CG42279 抗体
Dmel\\CG42279 抗体
Dmel_CG7555 抗体
Dmel_CG32184 抗体
DNedd4 抗体
dNedd4 抗体
dNedd4-1 抗体
E430025J12Rik 抗体
GB16853 抗体
mKIAA0093 抗体
nedd4 抗体
NEDD4 抗体
Nedd4 抗体
NEDD4-1 抗体
Nedd4-1 抗体
Nedd4a 抗体
RPF1 抗体
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