NEDD4-2 抗体
(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
Recommended next Filters:
90 results
Carrier-free
NEDD4L
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC, FACS, ICC
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our NEDD4-2 抗体
: "Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1157-65, (2008) (PubMed).
Aliases for NEDD4-2 抗体
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L) 抗体NEDD4L (LOC776799) 抗体
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog (nedd4l.S) 抗体
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (Nedd4l) 抗体
neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l) 抗体
1300012C07Rik 抗体
hNEDD4-2 抗体
nedd4 抗体
NEDD4 抗体
NEDD4-2 抗体
nedd4-2 抗体
Nedd4-2 抗体
NEDD4.2 抗体
Nedd4b 抗体
RSP5 抗体
您还需要查找其他产品吗？
You are here:
