This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq, Jul 2008].
Elbatsh, Kim, Eeftens, Raaijmakers, van der Weide, García-Nieto, Bravo, Ganji, Uit de Bos, Teunissen, Medema, de Wit, Haering, Dekker, Rowland: "Distinct Roles for Condensin's Two ATPase Sites in Chromosome Condensation." in: Molecular cell, Vol. 76, Issue 5, pp. 724-737.e5, (2019) (PubMed).
Dávalos, Súarez-López, Castaño, Messent, Abasolo, Fernandez, Guerra-Moreno, Espín, Armengol, Musulen, Ariza, Sayós, Arango, Schwartz: "Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target." in: The Journal of biological chemistry, Vol. 287, Issue 52, pp. 43472-81, (2012) (PubMed).
Torres-Rosell, De Piccoli, Cordon-Preciado, Farmer, Jarmuz, Machin, Pasero, Lisby, Haber, Aragón: "Anaphase onset before complete DNA replication with intact checkpoint responses." in: Science (New York, N.Y.), Vol. 315, Issue 5817, pp. 1411-5, (2007) (PubMed).
Cabello, Eliseeva, He, Youssoufian, Plon, Brinkley, Belmont: "Cell cycle-dependent expression and nucleolar localization of hCAP-H." in: Molecular biology of the cell, Vol. 12, Issue 11, pp. 3527-37, (2001) (PubMed).
Aliases for NCAPH 抗体
non-SMC condensin I complex subunit H (NCAPH) 抗体 non-SMC condensin I complex, subunit H (ncaph) 抗体 condensin complex subunit 2 (LOC708975) 抗体 non-SMC condensin I complex, subunit H (NCAPH) 抗体 non-SMC condensin I complex subunit H S homeolog (ncaph.S) 抗体 non-SMC condensin I complex, subunit H (Ncaph) 抗体 A730011O11Rik 抗体 BRRN1 抗体 brrn1 抗体 Brrn1 抗体 CAP-H 抗体 cap-h 抗体 HCAP-H 抗体 mKIAA0074 抗体 NCAPH 抗体 si:dkeyp-86b9.4 抗体 zgc:158618 抗体