The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008].
Jiu, Kumari, Fenix, Schaible, Liu, Varjosalo, Krishnan, Burnette, Lappalainen: "Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles." in: Current biology : CB, Vol. 29, Issue 1, pp. 81-92.e5, (2019) (PubMed).
Nishioka, Kohno, Tani, Yanaihara, Tomizawa, Otsuka, Sasaki, Kobayashi, Niki, Maeshima, Sekido, Minna, Sone, Yokota: "MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 19, pp. 12269-74, (2002) (PubMed).