The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011].
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Aliases for MSH3 抗体
mutS homolog 3 (MSH3) 抗体 mutS homolog 3 (Msh3) 抗体 DNA mismatch repair protein MSH3 (MSH3) 抗体 homolog of DNA mismatch repair protein MSH3 (MSH3) 抗体 mismatch repair protein (MSH3) 抗体 ATMSH3 抗体 D13Em1 抗体 DUP 抗体 homolog of DNA mismatch repair protein MSH3 抗体 M7J2.90 抗体 M7J2_90 抗体 MRP1 抗体 Rep-3 抗体 Rep3 抗体