Mps1 抗体
(Mps1 (TTK))
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009].
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Latest Publications for our Mps1 抗体
: "Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients." in: Journal of translational medicine, Vol. 12, pp. 84, (2014) (PubMed).: "High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint." in: Carcinogenesis, Vol. 32, Issue 3, pp. 305-11, (2011) (PubMed).
: "Structure and evolution of mammalian ribosomal proteins." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 73, Issue 11-12, pp. 933-47, (1996) (PubMed).
Aliases for Mps1 抗体
Ttk protein kinase (Ttk) 抗体TTK protein kinase (TTK) 抗体
ttk protein kinase (ttk) 抗体
AL022661 抗体
CT96 抗体
ESK 抗体
esk 抗体
Esk1 抗体
MPH1 抗体
MPS1 抗体
Mps1 抗体
mps1 抗体
MPS1L1 抗体
ncp 抗体
PYT 抗体
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