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MMP17 产品

(Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT)\; a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth\; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008].

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Featured MMP17 Categories

MMP17 抗体

High quality antibodies with extensive validation data.

MMP17 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MMP17 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MMP17 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), ICC, IF
Validations
  • (4)
Cat. No. ABIN2856073
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN657916
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN735533
Quantity 100 μL
Datasheet Datasheet

Recommended MMP17 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968478
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968479
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957691
Quantity 96 tests
Datasheet Datasheet

Recommended MMP17 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119898
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083811
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412518
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MMP17 Products

Liang, Xiao, Long, Liu, Li, Liu, Yang: "Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy." in: International journal of molecular medicine, Vol. 40, Issue 6, pp. 1781-1791, (2018) (PubMed).

Jung, Römer, Keyszer, Lein, Kristiansen, Schnorr, Loening, Jung: "mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue." in: The Prostate, Vol. 55, Issue 2, pp. 89-98, (2003) (PubMed).

Wang, Johnson, Ye, Dyer: "Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain." in: The Journal of biological chemistry, Vol. 274, Issue 46, pp. 33043-9, (2000) (PubMed).

Synonyms and alternative names related to MMP17

matrix metallopeptidase 17 (MMP17), interleukin enhancer binding factor 3 (ILF3), matrix metallopeptidase 17 (Mmp17), matrix metallopeptidase 17a (mmp17a), CBTF, DRBF, DRBP76, MMP4, mmp17, MPHOSPH4, MPP4, MT4-MMP, MT4MMP, MTMMP4, NF-AT-90, NF90, NF90a, NF90b, NF110, NF110b, NFAR, NFAR-1, NFAR2, TCP80, TCP110

Protein level used designations for MMP17

  • MMP-17
  • MT-MMP 4
  • MT4MMP
  • MTMMP4
  • matrix metalloproteinase 17 (membrane-inserted)
  • matrix metalloproteinase-17
  • membrane-type matrix metalloproteinase 4
  • membrane-type-4 matrix metalloproteinase
  • M-phase phosphoprotein 4
  • double-stranded RNA-binding protein, 76 kD
  • dsRNA binding protein NFAR-2/MPP4
  • interleukin enhancer-binding factor 3
  • nuclear factor associated with dsRNA
  • nuclear factor of activated T-cells 90 kDa
  • nuclear factor of activated T-cells, 90 kD
  • translational control protein 80
  • matrix metalloproteinase 17
  • membrane type-4 matrix metalloproteinase
  • matrix metallopeptidase 17 (membrane-inserted)
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