MLLT11 抗体
(Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1\;11)(q21\;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008].
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Latest Publications for our MLLT11 抗体
: "MLLT11/AF1q is differentially expressed in maturing neurons during development." in: Gene expression patterns : GEP, Vol. 15, Issue 2, pp. 80-7, (2014) (PubMed).: "AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells." in: PLoS ONE, Vol. 7, Issue 6, pp. e39968, (2012) (PubMed).
: "AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway." in: Blood, Vol. 118, Issue 7, pp. 1784-96, (2011) (PubMed).
: "Identification of the functional role of AF1Q in the progression of breast cancer." in: Breast cancer research and treatment, Vol. 111, Issue 1, pp. 65-78, (2008) (PubMed).
: "Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway." in: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3160-8, (2008) (PubMed).
Aliases for MLLT11 抗体
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11) 抗体MLLT11, transcription factor 7 cofactor (MLLT11) 抗体
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (Mllt11) 抗体
MLLT11, transcription factor 7 cofactor (Mllt11) 抗体
MLLT11, transcription factor 7 cofactor (mllt11) 抗体
AF1Q 抗体
Af1q 抗体
AI839562 抗体
fc23g02 抗体
RGD1305525 抗体
RP11-316M1.10 抗体
si:ch211-210h11.4 抗体
wu:fc23g02 抗体
Zfp692 抗体
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