Mitogen-Activated Protein Kinase 产品
(Mitogen-Activated Protein Kinase (MAPK))
Categories
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the MAPK/ERK cascade. Depending on the cellular context, this cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The the MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. Many of the substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC)\; as well as in the fragmentation of the Golgi apparatus during mitosis. Phosphorylates microtubule-associated protein 2 (MAP2), myelin basic protein (MBP), and Elk-1. Activated by M phase promoting factor (MPF).
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Featured Mitogen-Activated Protein Kinase Categories
Mitogen-Activated Protein Kinase 抗体
High quality antibodies with extensive validation data.
Mitogen-Activated Protein Kinase ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended Mitogen-Activated Protein Kinase 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN550154
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Frog, Human, Mouse, Primate, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN550190
Quantity
100 μL
Datasheet
Datasheet
Recommended Mitogen-Activated Protein Kinase ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968637
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative DNA-Binding ELISA
Validations
Cat. No.
ABIN2866275
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Competition ELISA
Validations
Cat. No.
ABIN1059979
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our Mitogen-Activated Protein Kinase Products
: ""RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway." in: FEBS letters, Vol. 588, Issue 15, pp. 2398-406, (2014) (PubMed).: "Molecular recognitions in the MAP kinase cascades." in: Cellular signalling, Vol. 15, Issue 5, pp. 455-62, (2003) (PubMed).
: "Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases." in: Science (New York, N.Y.), Vol. 298, Issue 5600, pp. 1911-2, (2002) (PubMed).
: "Molecular psychology: roles for the ERK MAP kinase cascade in memory." in: Annual review of pharmacology and toxicology, Vol. 42, pp. 135-63, (2002) (PubMed).
Synonyms and alternative names related to Mitogen-Activated Protein Kinase
mitogen-activated protein kinase (Tc00.1047053506229.10), mitogen-activated protein kinase (Tb927.6.1780), mitogen-activated protein kinase (Tb927.8.3770), mitogen-activated protein kinase 1 S homeolog (mapk1.S), erk, erk2, ert1, mapk, mapk1, mapk1a, mapk2, mpk1, p42mapk, prkm1, prkm2, Tb06.28P18.710, Tb08.10J17.560, xp42Protein level used designations for Mitogen-Activated Protein Kinase
- mitogen-activated protein kinase
- MAP kinase
- mitogen-activated protein kinase 1a
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