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Minichromosome Maintenance Deficient 4 蛋白

(Minichromosome Maintenance Deficient 4 (MCM4))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].

3 results :

MCM4 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Pubmed 1 reference
产品编号 ABIN1310553
 
MCM4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725632
 
MCM4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725633
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Antibody Production (AbP)
    • Standard (STD)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • ELISA
    • Western Blotting (WB)
  • 适用
    • Human
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-863
    • Transcript Variant 1
    • Transcript Variant 2
  • 标记
    • Myc-DYKDDDDK Tag
    • GST tag
  • 蛋白类型
    • Recombinant
  • Supplier
    • OriGene
    • antibodies-online

Latest Publications for our Minichromosome Maintenance Deficient 4 蛋白

Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).

Aliases for Minichromosome Maintenance Deficient 4 蛋白

minichromosome maintenance complex component 4 L homeolog (mcm4.L) 蛋白
minichromosome maintenance complex component 4 S homeolog (mcm4.S) 蛋白
minichromosome maintenance complex component 4 (MCM4) 蛋白
minichromosome maintenance complex component 4 (mcm4) 蛋白
minichromosome maintenance complex component 4 (Mcm4) 蛋白
19G 蛋白
AI325074 蛋白
AU045576 蛋白
cb1025 蛋白
cdc21 蛋白
CDC21 蛋白
Cdc21 蛋白
CDC54 蛋白
fc12c09 蛋白
fj85g09 蛋白
hCdc21 蛋白
hm:zeh1616 蛋白
mcdc21 蛋白
Mcmd4 蛋白
mKIAA4003 蛋白
NKCD 蛋白
NKGCD 蛋白
P1-CDC21 蛋白
wu:fc12c09 蛋白
wu:fj85g09 蛋白
zeh1616 蛋白
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