MCM4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all MCM4 蛋白
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MCM4 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human MCM4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MCM4 蛋白
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Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) protein (GST tag)
MCM4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Minichromosome Maintenance Deficient 4 (MCM4) (AA 267-366) protein (GST tag)MCM4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-863) protein (His tag)Crystallography grade MCM4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-862) protein (His tag)Crystallography grade MCM4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Minichromosome Maintenance Deficient 4 (MCM4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MCM4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
- 别名
- Mcm4 (MCM4 产品)
- 别名
- cdc21 Protein, CDC21 Protein, CDC54 Protein, NKCD Protein, NKGCD Protein, P1-CDC21 Protein, hCdc21 Protein, 19G Protein, AI325074 Protein, AU045576 Protein, Cdc21 Protein, Mcmd4 Protein, mKIAA4003 Protein, mcdc21 Protein, cb1025 Protein, fc12c09 Protein, fj85g09 Protein, hm:zeh1616 Protein, wu:fc12c09 Protein, wu:fj85g09 Protein, zeh1616 Protein, minichromosome maintenance complex component 4 L homeolog Protein, minichromosome maintenance complex component 4 S homeolog Protein, minichromosome maintenance complex component 4 Protein, mcm4.L Protein, mcm4.S Protein, MCM4 Protein, mcm4 Protein, Mcm4 Protein
- 背景
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
- 分子量
- 96.4 kDa
- NCBI登录号
- NP_877423
- 途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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