MIB1 抗体
(Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
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Latest Publications for our MIB1 抗体
: "Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA." in: Cell reports, Vol. 25, Issue 13, pp. 3811-3827.e7, (2018) (PubMed).
: "Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods." in: The EMBO journal, Vol. 30, Issue 8, pp. 1520-35, (2011) (PubMed).
: "Notch signalling: a simple pathway becomes complex." in: Nature reviews. Molecular cell biology, Vol. 7, Issue 9, pp. 678-89, (2006) (PubMed).
: "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta." in: Developmental cell, Vol. 4, Issue 1, pp. 67-82, (2003) (PubMed).
: "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 46980-6, (2002) (PubMed).
: "Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods." in: The EMBO journal, Vol. 30, Issue 8, pp. 1520-35, (2011) (PubMed).
: "Notch signalling: a simple pathway becomes complex." in: Nature reviews. Molecular cell biology, Vol. 7, Issue 9, pp. 678-89, (2006) (PubMed).
: "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta." in: Developmental cell, Vol. 4, Issue 1, pp. 67-82, (2003) (PubMed).
: "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 46980-6, (2002) (PubMed).
Aliases for MIB1 抗体
mindbomb E3 ubiquitin protein ligase 1 (MIB1) 抗体mindbomb E3 ubiquitin protein ligase 1 (Mib1) 抗体
mindbomb E3 ubiquitin protein ligase 1 L homeolog (mib1.L) 抗体
mindbomb E3 ubiquitin protein ligase 1 (mib1) 抗体
mind bomb 1 (mib1) 抗体
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D-mib 抗体
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