HSD11B1 蛋白
(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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14 results
HSD11B1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
HSD11B1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
HSD11B1
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
HSD11B1
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
HSD11B1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
HSD11B1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
HSD11B1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
HSD11B1
宿主: Golden Syrian Hamster
宿主: 酵母菌
Recombinant
> 90 %
ELISA
Aliases for HSD11B1 蛋白
hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1) 蛋白hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b) 蛋白
hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L) 蛋白
hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1) 蛋白
11-beta-HSD1 蛋白
11-DH 蛋白
CORTRD2 蛋白
HDL 蛋白
HSD11 蛋白
hsd11 蛋白
HSD11B 蛋白
hsd11b 蛋白
HSD11L 蛋白
LRRGT00065 蛋白
SDR26C1 蛋白
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