Mesothelin 蛋白
(Mesothelin (MSLN))
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Mesothelin Protein (MSLN) (AA 296-598) (Fc Tag) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 296-598) (His tag) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 296-598) (His tag) | Cynomolgus | 人细胞 |
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| Mesothelin Protein (MSLN) (AA 298-600) (His tag) | 小鼠 | 人细胞 |
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| Mesothelin Protein (MSLN) (AA 1-375) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| Mesothelin Protein (MSLN) (AA 1-375) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| Mesothelin Protein (MSLN) (Fc Tag,His tag) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) | 人 | Mammalian Cells |
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| Mesothelin Protein (MSLN) (AA 296-591) (His tag) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 488-600) (hFc Tag) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 296-580) (His-Avi Tag,PE) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 296-600) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 298-600) (His tag) | 大鼠 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (His tag,Biotin,AVI tag) | Cynomolgus | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (hFc-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (His tag,Biotin,AVI tag) | 小鼠 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (AA 37-606) | 人 | 大肠杆菌（E. Coli） |
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| Mesothelin Protein (MSLN) (AA 34-514) (His tag) | Cynomolgus | HEK-293 Cells |
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| Mesothelin Protein (MSLN) (DYKDDDDK Tag,Strep Tag) | 人 | HEK-293 Cells |
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Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- ELISA (ELISA: 所列应用)
- Imm (Immunogen: 所列应用)
- cryo-EM (Cryogenic electron microscopy: 所列应用)
- PhD (Phage Display: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Synthetic Nanodisc
Latest Publications for our Mesothelin 蛋白
: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." in: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).
: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
: "Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer." in: Molecular cancer therapeutics, Vol. 7, Issue 2, pp. 286-96, (2008) (PubMed).
: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
: "Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer." in: Molecular cancer therapeutics, Vol. 7, Issue 2, pp. 286-96, (2008) (PubMed).
Aliases for Mesothelin 蛋白
mesothelin (MSLN) 蛋白mesothelin (Msln) 蛋白
mesothelin (LOC611363) 蛋白
mesothelin (LOC100524016) 蛋白
MPF 蛋白
MSLN 蛋白
SMRP 蛋白
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