Mesothelin 蛋白
(Mesothelin (MSLN))
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
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71 results
MSLN
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MSLN
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MSLN
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MSLN
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MSLN
宿主: 大鼠
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MSLN
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MSLN
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
MSLN
宿主: 小鼠
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, ELISA, Imm, AcA
Active
Latest Publications for our Mesothelin 蛋白
: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." in: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
: "Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer." in: Molecular cancer therapeutics, Vol. 7, Issue 2, pp. 286-96, (2008) (PubMed).
Aliases for Mesothelin 蛋白
mesothelin (MSLN) 蛋白mesothelin (Msln) 蛋白
mesothelin (LOC611363) 蛋白
mesothelin (LOC100524016) 蛋白
MPF 蛋白
MSLN 蛋白
SMRP 蛋白
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- MERTK 蛋白
- Merlin 蛋白
- Meprin B 蛋白
- MEPCE 蛋白
- MEP1A 蛋白
- MEOX2 蛋白
- MEOX1 蛋白
- Meningioma 1 蛋白
- Menin 蛋白
- MEMO1 蛋白
- Membrane-Spanning 4-Domains, Subfamily A, Member 8 蛋白
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- Melanocortin 5 Receptor 蛋白
- MEK1 蛋白
- MESP1 蛋白
- MEST 蛋白
- Metabotropic Glutamate Receptor 1 蛋白
- Metabotropic Glutamate Receptor 3 蛋白
- Metabotropic Glutamate Receptor 4 蛋白
- Metabotropic Glutamate Receptor 5 蛋白
- Metabotropic Glutamate Receptor 6 蛋白
- Metalloproteinase Inhibitor 2 蛋白
- Metallothionein 蛋白
- Metallothionein 1F 蛋白
- Metallothionein 1X 蛋白
- Metallothionein 2 蛋白
- METAP1 蛋白
- METAP2 蛋白
- Metaxin 1 蛋白
- Methyltransferase Like 19 蛋白
- Methyltransferase Like 21B 蛋白
- Methyltransferase Like 21D 蛋白
- METRN 蛋白
- METRNL 蛋白
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