The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
Latest Publications for our MDS1 and EVI1 Complex Locus 抗体
Konrad, Karger, Hackl, Schwarzinger, Herbacek, Wieser: "Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes." in: Journal of leukocyte biology, Vol. 86, Issue 4, pp. 813-22, (2009) (PubMed).
Aliases for MDS1 and EVI1 Complex Locus 抗体
MDS1 and EVI1 complex locus (MECOM) 抗体 MDS1 and EVI1 complex locus (Mecom) 抗体 MDS1 and EVI1 complex locus (mecom) 抗体 MDS1 and EVI1 complex locus L homeolog (mecom.L) 抗体 MDS1 and EVI1 complex locus S homeolog (mecom.S) 抗体 AML1-EVI-1 抗体 D630039M04Rik 抗体 Evi-1 抗体 evi-1 抗体 EVI1 抗体 Evi1 抗体 evi1 抗体 evi1-B 抗体 im:7140716 抗体 Jbo 抗体 Mds 抗体 MDS1 抗体 Mds1 抗体 MDS1-EVI1 抗体 Mds1-Evi1 抗体 mecom 抗体 mecom-a 抗体 mecom-b 抗体 PRDM3 抗体 Prdm3 抗体 prdm3 抗体 xEvi-1 抗体 Znfpr1b1 抗体